CUDC-427
CUDC-427 (GDC-0917) is an orally active, pan-IAP antagonist used in cancer research. It has demonstrated pro-apoptotic activity in vitro and has shown efficacy in reducing tumor growth in various xenograft models in vivo, supporting its investigation as a potential therapeutic agent.
Product Specifications
CAS Number
1446182-94-0
Product Name Alternative
CIAP1, CUDC 427, CUDC427, CUDC-427, IAP, GDC0917, GDC-0917, GDC 0917
Field of Research
Cell Biology
Purity
98.99% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.54 mM) ; DMSO:45 mg/mL (79.69 mM)
Smiles
CN[C@@H] (C) C (=O) N[C@@H] (C1CCCCC1) C (=O) N1CCC[C@H]1C (=O) Nc1sc (nc1-c1ccccc1) -c1ncco1
Molecular Formula
C29H36N6O4S
Molecular Weight
564.7
Storage Conditions
-20°C
Notes
For research use only.
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