Defactinib hydrochloride
Defactinib hydrochloride is a potent and selective FAK inhibitor that suppresses autophosphorylation at Tyr397 in a time- and dose-dependent fashion. It is a valuable research tool for studying FAK's role in cancer cell migration, proliferation, and survival in both cellular and animal models of tumor progression.
Product Specifications
CAS Number
1073160-26-5
Product Name Alternative
Defactinib Hydrochloride, FAK, VS 6063 Hydrochloride, VS6063 Hydrochloride, VS-6063 hydrochloride, VS-6063 Hydrochloride, PF 04554878 hydrochloride, PF 04554878 Hydrochloride, PF04554878 Hydrochloride, PF-04554878 Hydrochloride
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.75% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (41.14 mM) ; H2O:0.1 mg/mL (0.18 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (0.91 mM)
Smiles
Cl.CNC (=O) c1ccc (Nc2ncc (c (NCc3nccnc3N (C) S (C) (=O) =O) n2) C (F) (F) F) cc1
Molecular Formula
C20H22ClF3N8O3S
Molecular Weight
546.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6175144-01 0.1 mL
RIPK4 (Receptor-Interacting Serine-Threonine Kinase 4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4) (FITC)
Sign In for Pricing
View Details MBS6175144-02 5x 0.1 mL
RIPK4 (Receptor-Interacting Serine-Threonine Kinase 4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4) (FITC)
Sign In for Pricing
View Details 
abx149420-01 50 µg
CKLF Like MARVEL Transmembrane Domain Containing 4 (CMTM4) Antibody
Sign In for Pricing
View Details abx149420-02 100 µg
CKLF Like MARVEL Transmembrane Domain Containing 4 (CMTM4) Antibody
Sign In for Pricing
View Details