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Dihydrofolic acid

Dihydrofolic acid (7,8-DHFA) is a key folate cycle intermediate that is enzymatically reduced to tetrahydrofolate by dihydrofolate reductase. It is widely used as a biochemical substrate in enzyme activity assays and for studying antifolate mechanisms in cancer and antimicrobial research, both in vitro and in cellular models.

Product Specifications

CAS Number

4033-27-6

Smiles

O=C1C2=C (NCC (CNC3=CC=C (C (N[C@@H] (CCC (O) =O) C (O) =O) =O) C=C3) =N2) NC (N) =N1

Molecular Formula

C19H21N7O6

Molecular Weight

443.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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