DS-437
DS-437 is a dual inhibitor of PRMT5 and PRMT7 (IC50: 6 μM), and also inhibits DNMT3A and DNMT3B at higher concentrations. It suppresses FOXP3 methylation and is used in vitro to study epigenetic regulation in immunology and oncology research.
Product Specifications
CAS Number
1674364-87-4
Field of Research
Epigenetics & Chromatin
Smiles
CCNC (=O) NCCSC[C@H]1O[C@H] ([C@H] (O) [C@@H]1O) n1cnc2c (N) ncnc12
Molecular Formula
C15H23N7O4S
Molecular Weight
397.45
Storage Conditions
-20°C
Notes
For research use only.
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