DTRIM24
DTRIM24 is a PROTAC-based degrader that selectively targets TRIM24 for ubiquitination and degradation by recruiting the von Hippel-Lindau E3 ligase. This bifunctional molecule is a valuable chemical probe for investigating TRIM24 biology in cancer research, applicable in both cellular and in vivo models to study oncogenic pathways.
Product Specifications
CAS Number
2170695-14-2
Product Name Alternative
EpigeneticReaderDomain, Epigenetic Reader Domain, dTRIM24, dTRIM-24, TRIM24
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.13% (May vary between batches)
Solubility
DMSO:90 mg/mL (80.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (2.96 mM) ; Ethanol:insoluble
Smiles
O (C1=C (NS (=O) (=O) C2=CC (C (NCCOCCOCCOCC (N[C@H] (C (=O) N3[C@H] (C (NCC4=CC=C (C=C4) C=5SC=NC5C) =O) C[C@@H] (O) C3) C (C) (C) C) =O) =O) =CC=C2) C=C6C (=C1) N (C) C (=O) N6C) C7=CC (OCCC) =CC=C7
Molecular Formula
C55H68N8O13S2
Molecular Weight
1113.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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