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(S, R, S) -AHPC-PEG4-NH2

This synthetic E3 ligase ligand-linker conjugate incorporates a VHL-targeting (S, R, S) -AHPC ligand connected via a tetraethylene glycol (PEG4) spacer. It serves as a key component in the construction of PROTACs and other bifunctional molecules for targeted protein degradation research, applicable in both cellular and in vivo studies to probe disease biology.

Product Specifications

CAS Number

2010159-57-4

Product Name Alternative

E3 ligase Ligand-Linker Conjugates 7, E3 ligase Ligand-Linker Conjugates 7 Free Base, AHPC-PEG4-NH2, Ligand for E3 Ligase, LigandforE3Ligase, VHL Ligand-Linker Conjugates 4, VHL, VH032-PEG4-NH2

Field of Research

Pharmacology & Drug Discovery

Purity

94.31% (May vary between batches)

Solubility

DMSO:153 mg/mL (230.48 mM)

Smiles

C ([C@@H] (NC (COCCOCCOCCOCCN) =O) [C@] (C) (C) C) (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C=3SC=NC3C) =O) C[C@@H] (O) C1

Molecular Formula

C32H49N5O8S

Molecular Weight

663.83

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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