(S, R, S) -AHPC-PEG4-NH2
This synthetic E3 ligase ligand-linker conjugate incorporates a VHL-targeting (S, R, S) -AHPC ligand connected via a tetraethylene glycol (PEG4) spacer. It serves as a key component in the construction of PROTACs and other bifunctional molecules for targeted protein degradation research, applicable in both cellular and in vivo studies to probe disease biology.
Product Specifications
CAS Number
2010159-57-4
Product Name Alternative
E3 ligase Ligand-Linker Conjugates 7, E3 ligase Ligand-Linker Conjugates 7 Free Base, AHPC-PEG4-NH2, Ligand for E3 Ligase, LigandforE3Ligase, VHL Ligand-Linker Conjugates 4, VHL, VH032-PEG4-NH2
Field of Research
Pharmacology & Drug Discovery
Purity
94.31% (May vary between batches)
Solubility
DMSO:153 mg/mL (230.48 mM)
Smiles
C ([C@@H] (NC (COCCOCCOCCOCCN) =O) [C@] (C) (C) C) (=O) N1[C@H] (C (NCC2=CC=C (C=C2) C=3SC=NC3C) =O) C[C@@H] (O) C1
Molecular Formula
C32H49N5O8S
Molecular Weight
663.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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