Edotecarin
Edotecarin is a potent small molecule inhibitor of topoisomerase I, exhibiting an IC50 of 50 nM for the suppression of single-strand DNA cleavage. It has been utilized in cancer research, demonstrating antitumor activity in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
174402-32-5
Field of Research
Molecular Biology
Smiles
O=C1C2=C3C (N (C=4C3=CC=C (O) C4) [C@@H]5O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]5O) =C6C (=C2C (=O) N1NC (CO) CO) C=7C (N6) =CC (O) =CC7
Molecular Formula
C29H28N4O11
Molecular Weight
608.55
Storage Conditions
-20°C
Notes
For research use only.
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