EHT 1610
EHT 1610 is a highly potent and selective DYRK1A/B inhibitor with sub-nanomolar IC50 values. It demonstrates anti-leukemic activity in research settings by disrupting cell cycle progression and promoting apoptosis in vitro, supporting its investigation in oncology and cell signaling studies.
Product Specifications
CAS Number
1425945-60-3
Product Name Alternative
DYRK2, DYRK1B, DYRK1A, DYRK3, CLK1, CLK2, Clk4, GSK-3α, GSK3α, GSK3β, GSK-3β, GSK3, EHT5372, EHT-5372, EHT 5372, EHT1610, EHT-1610, EHT 1610, p65, NFκB, NFkB, NF-kB, Tyrosinase
Field of Research
Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.27% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (11.74 mM)
Smiles
COC (=N) c1nc2ccc3ncnc (Nc4ccc (OC) cc4F) c3c2s1
Molecular Formula
C18H14FN5O2S
Molecular Weight
383.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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