CCX354
CCX354 is a potent and selective small molecule antagonist of the CCR1 chemokine receptor, exhibiting anti-inflammatory properties. It has been utilized in research models of rheumatoid arthritis, demonstrating efficacy in both in vitro binding assays and in vivo studies of inflammatory disease.
Product Specifications
CAS Number
1010073-75-2
Product Name Alternative
CCR1 antagonist 1, CCR1, CCX 354, CCX354, CCX-354
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.28% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.43 mM) ; DMSO:60 mg/mL (132.77 mM)
Smiles
COc1cc (ccc1Cl) N1CCN (CC1) C (=O) Cn1nc (-c2ncc[nH]2) c2cccnc12
Molecular Formula
C22H22ClN7O2
Molecular Weight
451.91
Storage Conditions
-20°C
Notes
For research use only.
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