Vactosertib Hydrochloride
Vactosertib Hydrochloride (EW-7197 Hydrochloride) is an orally bioavailable, ATP-competitive inhibitor of ALK5 (TGF-β receptor I) . It demonstrates anti-metastatic and anticancer activity in vitro and in vivo, and research shows it can sensitize pancreatic cancer cells to gemcitabine by inhibiting cell viability.
Product Specifications
CAS Number
1352610-25-3
Product Name Alternative
EW7197 Hydrochloride, EW-7197 Hydrochloride, EW 7197 Hydrochloride, NOV 1301 Hydrochloride, NOV1301 Hydrochloride, ALK5, Vactosertib Hydrochloride, TEW 7197 Hydrochloride, TEW7197 Hydrochloride, TEW-7197 Hydrochloride
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.03% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.18 mM) ; H2O:20 mg/mL (45.88 mM) ; DMSO:100 mg/mL (229.42 mM)
Smiles
Cl.FC=1C=CC=CC1NCC2=NC (C3=NC (=CC=C3) C) =C (N2) C=4C=CC5=NC=NN5C4
Molecular Formula
C22H19ClFN7
Molecular Weight
435.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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