Fidarestat
Fidarestat (SNK-860) is a potent and selective aldose reductase inhibitor with IC50 values of 26 nM (aldose reductase), 33 μM (AKR1B10), and 1.8 μM (V301L AKR1B10) . It is a valuable research tool for studying diabetic complications, such as neuropathy and cataracts, in both in vitro and in vivo models.
Product Specifications
CAS Number
136087-85-9
Product Name Alternative
Fidarestat, AKR1B10, Aldose reductase, V301L AKR1B10, SNK 860, SNK860, SNK-860
Field of Research
Metabolism Research
Solubility
DMSO:100 mg/mL (358.14 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.33 mM)
Smiles
O=C1[C@]2 (C=3C (O[C@H] (C (N) =O) C2) =CC=C (F) C3) NC (=O) N1
Molecular Formula
C12H10FN3O4
Molecular Weight
279.22
Storage Conditions
-20°C
Notes
For research use only.
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