Filibuvir
Filibuvir (PF-00868554) is a potent, noncovalent inhibitor of the hepatitis C virus NS5B RNA-dependent RNA polymerase. It demonstrates antiviral activity against HCV genotypes 1a and 1b in replicon assays with EC50 values of 59 nM. This compound is a valuable tool for investigating HCV replication mechanisms and evaluating antiviral strategies in vitro.
Product Specifications
CAS Number
877130-28-4
Product Name Alternative
RNA Synthesis, RNA-dependent RNA polymerase, RNASynthesis, PF-00868554, PF00868554, PF 00868554, DNASynthesis, DNA/RNA Synthesis, DNA Synthesis, HCV NS5B, HCVProtease, HCV Protease, Filibuvir
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry
Purity
98.76% (May vary between batches)
Solubility
DMSO:40 mg/mL (79.42 mM)
Smiles
CCc1cc (CC[C@@]2 (CC (O) =C (Cc3nc4nc (C) cc (C) n4n3) C (=O) O2) C2CCCC2) cc (CC) n1
Molecular Formula
C29H37N5O3
Molecular Weight
503.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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