Fosnetupitant
Fosnetupitant is a prodrug of netupitant, designed as a methylene phosphate derivative. It exhibits high-affinity binding to the human NK1 receptor with a pKi of 9.5, making it a relevant tool for studying antiemetic mechanisms in both in vitro and in vivo preclinical research.
Product Specifications
CAS Number
1703748-89-3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
N (C (C (C) (C) C1=CC (C (F) (F) F) =CC (C (F) (F) F) =C1) =O) (C) C=2C (=CC (=NC2) N3CC[N+] (COP (=O) ([O-]) O) (C) CC3) C4=C (C) C=CC=C4
Molecular Formula
C31H35F6N4O5P
Molecular Weight
688.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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