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FT827

FT827 is a covalent, selective USP7 inhibitor (Ki=4.2 μM, Kd=7.8 μM) that targets the catalytic site of its autoinhibited conformation. This compound is a valuable research tool for investigating USP7's role in oncology, supporting both in vitro biochemical assays and cellular mechanism-of-action studies.

Product Specifications

CAS Number

1959537-86-0

Product Name Alternative

FT 827, FT827, FT-827, USP7

Field of Research

Cell Biology, Molecular Biology, Protein Biochemistry

Purity

98.63% (May vary between batches)

Solubility

DMSO:80 mg/mL (145.82 mM)

Smiles

Cn1ncc2c1ncn (CC1 (O) CCN (CC1) C (=O) c1ccc (cc1) -c1ccccc1NS (=O) (=O) C=C) c2=O

Molecular Formula

C27H28N6O5S

Molecular Weight

548.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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