FT827
FT827 is a covalent, selective USP7 inhibitor (Ki=4.2 μM, Kd=7.8 μM) that targets the catalytic site of its autoinhibited conformation. This compound is a valuable research tool for investigating USP7's role in oncology, supporting both in vitro biochemical assays and cellular mechanism-of-action studies.
Product Specifications
CAS Number
1959537-86-0
Product Name Alternative
FT 827, FT827, FT-827, USP7
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.63% (May vary between batches)
Solubility
DMSO:80 mg/mL (145.82 mM)
Smiles
Cn1ncc2c1ncn (CC1 (O) CCN (CC1) C (=O) c1ccc (cc1) -c1ccccc1NS (=O) (=O) C=C) c2=O
Molecular Formula
C27H28N6O5S
Molecular Weight
548.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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