GNE-049
GNE-049 is a potent and selective small molecule inhibitor of CREB-binding protein (CBP), demonstrating an IC50 of 1.1 nM. It effectively suppresses BRET/BRD4 activity and inhibits prostate cancer cell proliferation in both in vitro and in vivo research models.
Product Specifications
CAS Number
1936421-41-8
Product Name Alternative
BRD41, BRET, CBP, Epigenetic Reader Domain, EpigeneticReaderDomain, GNE049, GNE-049, GNE 049
Field of Research
Epigenetics & Chromatin
Purity
98.67% (May vary between batches)
Solubility
DMSO:80 mg/mL (156.68 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.46 mM)
Smiles
O=C (N1CC=2C (=NN (C2CC1) C3CCOCC3) N4C=5C=C (C (=CC5CCC4) C=6C=NN (C6) C) C (F) F) C
Molecular Formula
C27H32F2N6O2
Molecular Weight
510.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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