GNE-272
GNE-272 is a potent and selective small molecule inhibitor of the CBP and EP300 bromodomains, with significantly lower activity against BRD4. It serves as a valuable in vivo chemical probe for investigating the roles of CBP/EP300 in oncology, immunology, and transcriptional regulation research.
Product Specifications
CAS Number
1936428-93-1
Field of Research
Epigenetics & Chromatin
Smiles
N (C=1C2=C (N (N1) [C@H]3CCOC3) CCN (C (C) =O) C2) C4=C (F) C=C (C=C4) C5=CN (C) N=C5
Molecular Formula
C22H25FN6O2
Molecular Weight
424.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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