GNE-618
GNE-618 is a potent, orally bioavailable inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with an IC50 of 6 nM. It depletes cellular NAD+, leading to tumor cell death, and has demonstrated anti-tumor activity in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
1362151-42-5
Field of Research
Metabolism Research
Smiles
FC (F) (F) c1cccc (c1) S (=O) (=O) c1ccc (CNC (=O) c2cnc3[nH]ncc3c2) cc1
Molecular Formula
C21H15F3N4O3S
Molecular Weight
460.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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