PF-06263276
PF-06263276 is a potent and selective pan-JAK inhibitor, demonstrating IC50 values of 2.2 nM (JAK1), 23.1 nM (JAK2), 59.9 nM (JAK3), and 29.7 nM (TYK2) . This small molecule is a valuable research tool for investigating JAK/STAT signaling in autoimmune and inflammatory disease models, both in cellular and preclinical studies.
Product Specifications
CAS Number
1421502-62-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CCc1cc (O) c (F) cc1-c1ccc2c (n[nH]c2c1) -c1nc2CCN (Cc2[nH]1) C (=O) c1cnc (cn1) N1CCCCC1
Molecular Formula
C31H31FN8O2
Molecular Weight
566.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog