Darigabat
Darigabat (PF-06372865) is an orally bioavailable, selective GABAA receptor modulator with anxiolytic properties, showing high affinity for α2-containing subtypes. It is utilized in preclinical research for investigating anxiety disorders and epilepsy, supported by in vivo models demonstrating its efficacy.
Product Specifications
CAS Number
1614245-70-3
Product Name Alternative
PF 06372865, PF06372865, PF-06372865, PF-6372865, α2 PAM, α2, α1 PAM, GABAReceptor, GABA Receptor, GABAA, CVL-865
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.42% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.54 mM) ; DMSO:30 mg/mL (68.11 mM)
Smiles
CCn1cnc2c (cnnc12) -c1ccc (F) c (c1) -c1ccc (cc1OC) S (=O) (=O) CC
Molecular Formula
C22H21FN4O3S
Molecular Weight
440.49
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS965355-01 0.02 mg (E-Coli)
Recombinant Mouse Adenylosuccinate synthetase isozyme 2 (Adss)
Sign In for Pricing
View Details MBS965355-02 0.02 mg (Yeast)
Recombinant Mouse Adenylosuccinate synthetase isozyme 2 (Adss)
Sign In for Pricing
View Details MBS965355-03 0.1 mg (E-Coli)
Recombinant Mouse Adenylosuccinate synthetase isozyme 2 (Adss)
Sign In for Pricing
View Details MBS965355-04 0.1 mg (Yeast)
Recombinant Mouse Adenylosuccinate synthetase isozyme 2 (Adss)
Sign In for Pricing
View Details