PhiKan 083 hydrochloride
PhiKan 083 hydrochloride is a carbazole-based small molecule that binds and stabilizes the p53 Y220C mutant surface cavity with a Kd of 167 μM, and exhibits a similar binding affinity (Kd: 150 μM) in Ln229 glioblastoma cells. This compound serves as a research tool for studying p53 reactivation in cancer biology, applicable in both biochemical and cellular assays.
Product Specifications
CAS Number
1050480-30-2
Field of Research
Cell Biology
Smiles
Cl.CCn1c2ccccc2c2cc (CNC) ccc12
Molecular Formula
C16H19ClN2
Molecular Weight
274.79
Storage Conditions
-20°C
Notes
For research use only.
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