PKI-166
PKI-166 is a potent and selective oral EGF-R tyrosine kinase inhibitor (IC50: 0.7 nM) . It has demonstrated efficacy in inhibiting the growth and metastasis of various human cancer cell lines, including pancreatic cancer, in both in vitro and in vivo preclinical studies.
Product Specifications
CAS Number
187724-61-4
Product Name Alternative
EGFR tyrosine kinase, PKI 166, PKI166, PKI-166, VEGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.20% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (83.24 mM)
Smiles
C[C@@H] (Nc1ncnc2[nH]c (cc12) -c1ccc (O) cc1) c1ccccc1
Molecular Formula
C20H18N4O
Molecular Weight
330.38
Storage Conditions
-20°C
Notes
For research use only.
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