Pozanicline

Pozanicline is a selective partial agonist of α4β2 neuronal nicotinic acetylcholine receptors (nAChRs), with high affinity for α6β2 and α4α5β2 subtypes. It has demonstrated efficacy in reversing nicotine withdrawal-induced cognitive deficits in preclinical models, making it a candidate for research into novel therapies for nicotine addiction.