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Pregnenolone monosulfate sodium

Pregnenolone monosulfate sodium salt is the sodium salt of an endogenous neurosteroid. It modulates neuronal excitability by enhancing NMDA receptor and TRPM3 channel activity while potentially inhibiting GABA A receptors. This compound is used in vitro and in vivo to study neurosteroid signaling, synaptic plasticity, and calcium-dependent processes.

Product Specifications

CAS Number

1852-38-6

Product Name Alternative

3β-Hydroxy-5-pregnen-20-one monosulfate sodium, 3β-Hydroxy-5-pregnen-20-one monosulfate sodium salt, 3b-Hydroxy-5-pregnen-20-one monosulfate sodium, 3beta-Hydroxy-5-pregnen-20-one monosulfate sodium, CB1, Human Endogenous Metabolite, Pregnenolone monosulfate sodium, Pregnenolone monosulfate sodium salt

Field of Research

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

99.76% (May vary between batches)

Solubility

H2O:2 mg/mL (4.78 mM) ; DMSO:80 mg/mL (191.15 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.88 mM)

Smiles

C[C@@]12[C@]3 ([H]) [C@] (CC=C1C[C@H] (CC2) OS (=O) ([O-]) =O) ([H]) [C@@]4 ([H]) [C@] (CC3) ([C@H] (CC4) C (C) =O) C.[Na+]

Molecular Formula

C21H31NaO5S

Molecular Weight

418.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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