Pyronaridine tetraphosphate
Pyronaridine tetraphosphate is an orally active mannitol adduct that inhibits DNA topoisomerase II and exhibits antimalarial, antitumor, and anti-echinococcal activity. Research applications include in vitro studies against Plasmodium falciparum and in vivo models for investigating its potential to attenuate viral infections such as Ebola.
Product Specifications
CAS Number
76748-86-2
Product Name Alternative
Pyronaridine, Pyronaridine tetraphosphate, topoisomerase II
Field of Research
Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:10 mg/mL (10.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.1 mM) ; H2O:20 mg/mL (21.98 mM)
Smiles
O=P (O) (O) O.ClC (C=CC1=C2NC3=CC (CN4CCCC4) =C (O) C (CN5CCCC5) =C3) =CC1=NC6=C2N=C (OC) C=C6.O=P (O) (O) O.O=P (O) (O) O.O=P (O) (O) O
Molecular Formula
C29H44ClN5O18P4
Molecular Weight
910.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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