R121919
R121919 (NBI30775) is a potent small molecule antagonist of the corticotropin-releasing factor receptor 1 (CRF1), also exhibiting activity at the CRF2 receptor and CRF-binding proteins. Its antidepressant and anxiolytic properties make it a valuable research tool for investigating stress-related disorders in both in vitro binding assays and in vivo behavioral models.
Product Specifications
CAS Number
195055-03-9
Product Name Alternative
R 121919, R-121919, R121919, NBI 30775, NBI30775, NBI-30775, CRF2, CRF1
Field of Research
Pharmacology & Drug Discovery
Purity
99.75% (May vary between batches)
Solubility
DMSO:5 mg/mL (13.14 mM) ; Ethanol:80 mg/mL (210.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.63 mM)
Smiles
CCCN (CCC) c1cc (C) nc2c (c (C) nn12) -c1cnc (cc1C) N (C) C
Molecular Formula
C22H32N6
Molecular Weight
380.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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