Radicicol
Radicicol (Monorden) is a natural Hsp90 inhibitor that binds its ATPase domain, inducing client protein degradation via the proteasome. It is widely used in cancer research to study tumor cell proliferation in vitro and has demonstrated anti-malarial and anti-inflammatory activity in research models by modulating p38 kinase and NF-κB signaling pathways.
Product Specifications
CAS Number
12772-57-5
Product Name Alternative
Monorden
Field of Research
Cardiovascular Research, Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
HSP90 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 8 mg/ml) .
Smiles
C[C@@H]1C[C@@H]2[C@H] (O2) /C=C\C=C\C (=O) CC3=C (C (=CC (=C3Cl) O) O) C (=O) O1
Molecular Formula
C18H17ClO6
Molecular Weight
364.78
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(1aR,2Z,4E,14R,15aR) -8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12 (7H) -dione
Available Sizes
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