Rheb inhibitor NR1
NR1 is a small molecule inhibitor that selectively targets Rheb and mTORC1, suppressing pS6K1 T389 phosphorylation while enhancing pAKT S473 phosphorylation. This tool compound is used in vitro and in vivo to study mTOR signaling dynamics in cancer and metabolic research.
Product Specifications
CAS Number
2216763-38-9
Product Name Alternative
MTORC1, Rheb inhibitor NR1, Rheb inhibitor NR-1
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.46 mM) ; DMSO:50 mg/mL (86.46 mM)
Smiles
CN (C) C (=O) c1ccc (Cn2c (cc3c (Br) cc (Sc4ccc (Cl) c (Cl) c4) cc23) C (O) =O) cc1
Molecular Formula
C25H19BrCl2N2O3S
Molecular Weight
578.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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