Rhosin
Rhosin is a potent and selective small molecule inhibitor of RhoA subfamily GTPases, binding specifically to RhoA (Kd ~0.4 μM) to disrupt RhoA-GEF interactions. It has been utilized in vitro to study RhoA-mediated cytoskeletal dynamics and cell adhesion, and has shown efficacy in inducing apoptosis in various cancer cell lines.
Product Specifications
CAS Number
1173671-63-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C ([C@H] (C (N/N=C/C1=CC2=C (C=C1) N=CC=N2) =O) N) C=3C=4C (NC3) =CC=CC4
Molecular Formula
C20H18N6O
Molecular Weight
358.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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