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Rilapladib

Rilapladib (SB 659032) is a potent and selective inhibitor of Lp-PLA2 (IC50 = 230 pM) and a platelet-activating factor receptor antagonist. This small molecule is a valuable research tool for investigating atherosclerosis and neuroinflammation in both cellular and animal models.

Product Specifications

CAS Number

412950-08-4

Product Name Alternative

Lp-PLA2, SB 659032, SB659032, SB-659032, Rilapladib

Field of Research

Metabolism Research

Purity

97.29% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.72 mM) ; DMSO:78 mg/mL (106.01 mM)

Smiles

COCCN1CCC (CC1) N (Cc1ccc (cc1) -c1ccc (cc1) C (F) (F) F) C (=O) Cn1c (SCc2cccc (F) c2F) cc (=O) c2ccccc12

Molecular Formula

C40H38F5N3O3S

Molecular Weight

735.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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