Rodatristat ethyl
Rodatristat ethyl (KAR5585) is a potent, orally bioavailable inhibitor of tryptophan hydroxylase 1 (TPH1) . By reducing peripheral serotonin (5-HT) synthesis, it has demonstrated efficacy in preclinical models of pulmonary arterial hypertension (PAH), supporting its investigation in cardiopulmonary research.
Product Specifications
CAS Number
1673571-51-1
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Smiles
C (OCC) (=O) [C@@H]1CC2 (CCN (CC2) C=3C=C (O[C@@H] (C (F) (F) F) C4=C (C=C (Cl) C=C4) C5=CC=CC=C5) N=C (N) N3) CN1
Molecular Formula
C29H31ClF3N5O3
Molecular Weight
590.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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