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Rogaratinib

Rogaratinib (BAY1163877) is a potent, selective, and orally bioavailable small molecule inhibitor targeting FGFR1, FGFR2, and FGFR3 kinase activity. It is widely used in preclinical research to investigate FGFR-driven pathologies, including in studies of cancer cell proliferation and tumor growth in both cellular and animal models.

Product Specifications

CAS Number

1443530-05-9

Product Name Alternative

BAY1163877, BAY-1163877, BAY 1163877, Inhibitor, FGFR4, FGFR3, FGFR2, FGFR, FGFR1, Fibroblast growth factor receptor, inhibit, Rogaratinib

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.54% (May vary between batches)

Solubility

DMSO:5.5 mg/mL (11.79 mM)

Smiles

COCc1c (CN2CCNC (=O) C2) n2ncnc (N) c2c1-c1cc2cc (C) cc (OC) c2s1

Molecular Formula

C23H26N6O3S

Molecular Weight

466.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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