RO 4938581
RO 4938581 is a potent and selective GABAA α5 inverse agonist, exhibiting high affinity for α5β3γ2 receptors (Ki = 4.6 nM) with significant selectivity over α1, α2, and α3 subtypes. This compound is a valuable research tool for investigating the role of α5-containing GABAA receptors in cognitive processes, supporting both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
883093-10-5
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
FC (F) c1ncn-2c1Cn1ncnc1-c1cc (Br) ccc-21
Molecular Formula
C13H8BrF2N5
Molecular Weight
352.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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