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RPR-260243

RPR-260243 is a novel small molecule that activates the HERG potassium channel. It can reverse the inhibition of HERG currents caused by dofetilide (IC50 = 58 nM), making it a valuable pharmacological tool for in vitro cardiac electrophysiology and arrhythmia research.

Product Specifications

CAS Number

668463-35-2

Field of Research

Pharmacology & Drug Discovery

Smiles

COc1ccc2nccc (C (=O) CC[C@@H]3CCN (CC#Cc4cc (F) cc (F) c4F) C[C@@H]3C (O) =O) c2c1

Molecular Formula

C28H25F3N2O4

Molecular Weight

510.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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