(S) -BI-1001
(S) -BI-1001 is the pharmacologically active S-enantiomer of BI-1001, functioning as an HIV-1 integrase inhibitor. It demonstrates antiviral activity with an IC50 of 28 nM and an EC50 of 450 nM in vitro, and binds with a Kd of 4.7 μM. This compound is a valuable research tool for studying HIV replication mechanisms and antiviral drug development.
Product Specifications
CAS Number
957889-73-5
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Smiles
[C@H] (C (O) =O) (OC) C1=C (C2=C (N=C1C) C=CC (Br) =C2) C3=CC=C (Cl) C=C3
Molecular Formula
C19H15BrClNO3
Molecular Weight
420.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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