SB-674042
SB-674042 is a potent, selective dual antagonist of orexin receptors OX1 and OX2, with IC50 values of 3.76 nM and 531 nM, respectively. It is a valuable research tool for studying orexin signaling in depression, sleep/wake regulation, and addiction, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
483313-22-0
Product Name Alternative
OX1, OX Receptor, OX2, OXReceptor, SB 674042, SB674042, SB-674042
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.82% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.23 mM) ; DMSO:20 mg/mL (44.59 mM)
Smiles
Cc1nc (C (=O) N2CCC[C@H]2Cc2nnc (o2) -c2ccccc2) c (s1) -c1ccccc1F
Molecular Formula
C24H21FN4O2S
Molecular Weight
448.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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