SB228357
SB228357 is a potent and selective 5-HT receptor antagonist, exhibiting pKi values of 6.9, 8.0, and 9.0 for the 5-HT2A, 5-HT2B, and 5-HT2C subtypes, respectively. This compound is a valuable research tool for investigating serotonergic signaling in both in vitro and in vivo models relevant to neuropharmacology and central nervous system disorders.
Product Specifications
CAS Number
181629-93-6
Product Name Alternative
SB228357, SB-228357, SB 228357, 5HTReceptor, 5-HT2B Receptor, 5-HT2C, 5-HT2B, 5-HT2C Receptor, 5-HT2A, 5-HT2A Receptor, 5HT Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.31% (May vary between batches)
Solubility
DMSO:38.9 mg/mL (90.18 mM)
Smiles
COc1cc2CCN (C (=O) Nc3cc (F) cc (c3) -c3cccnc3) c2cc1C (F) (F) F
Molecular Formula
C22H17F4N3O2
Molecular Weight
431.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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