SCH 546738
SCH 546738 is a potent and selective oral CXCR3 antagonist used in research. It has demonstrated efficacy in preclinical models, attenuating autoimmune disease progression and delaying allograft rejection in vivo. This small molecule is a valuable tool for studying chemokine receptor function in immunology and transplantation research.
Product Specifications
CAS Number
906805-42-3
Product Name Alternative
CXCR3, Human CXCR3, SCH546738, SCH-546738, SCH 546738
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.67% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.03 mM) ; DMSO:2 mg/mL (4.06 mM) ; H2O:< 1 mg/mL (2.03 mM, insoluble or slightly soluble.)
Smiles
ClC=1C (N2C[C@H] (CC) N (CC2) C3CCN (CC4=CC=C (Cl) C=C4) CC3) =NC (N) =C (C (N) =O) N1
Molecular Formula
C23H31Cl2N7O
Molecular Weight
492.45
Storage Conditions
-20°C
Notes
For research use only.
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