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SCH 563705

SCH 563705 is a potent, orally bioavailable dual antagonist of CXCR2 and CXCR1 chemokine receptors. It is a valuable research tool for investigating neutrophilic inflammation in models of acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD), both in vitro and in vivo.

Product Specifications

CAS Number

473728-58-4

Product Name Alternative

CXCR2, CXCR1, Mouse CXCR2, SCH 563705, SCH-563705

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.03% (May vary between batches)

Solubility

DMSO:100 mg/mL (235.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.75 mM)

Smiles

N (C1=C (N[C@H] (CC) C2=CC (C (C) C) =CO2) C (=O) C1=O) C3=C (O) C (C (N (C) C) =O) =CC=C3

Molecular Formula

C23H27N3O5

Molecular Weight

425.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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