SCH 563705
SCH 563705 is a potent, orally bioavailable dual antagonist of CXCR2 and CXCR1 chemokine receptors. It is a valuable research tool for investigating neutrophilic inflammation in models of acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD), both in vitro and in vivo.
Product Specifications
CAS Number
473728-58-4
Product Name Alternative
CXCR2, CXCR1, Mouse CXCR2, SCH 563705, SCH-563705
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
DMSO:100 mg/mL (235.03 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.75 mM)
Smiles
N (C1=C (N[C@H] (CC) C2=CC (C (C) C) =CO2) C (=O) C1=O) C3=C (O) C (C (N (C) C) =O) =CC=C3
Molecular Formula
C23H27N3O5
Molecular Weight
425.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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