SEC inhibitor KL-2
KL-2 is a potent and selective small molecule inhibitor of the super elongation complex (SEC), disrupting the AFF4-CCNT1 interaction with a Ki of 1.50 μM. This compound is a valuable chemical probe for studying transcriptional regulation in cancers and HIV latency reversal in both cellular and biochemical assays.
Product Specifications
CAS Number
900308-51-2
Product Name Alternative
KL 2, KL2, KL-2, SEC inhibitor KL-2, SEC
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.03% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (9.89 mM) ; DMSO:75 mg/mL (224.73 mM)
Smiles
Cc1ccc (Cl) cc1NC (=O) C (\O) =C\C (=O) c1ccc (F) cc1
Molecular Formula
C17H13ClFNO3
Molecular Weight
333.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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