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SEC inhibitor KL-2

KL-2 is a potent and selective small molecule inhibitor of the super elongation complex (SEC), disrupting the AFF4-CCNT1 interaction with a Ki of 1.50 μM. This compound is a valuable chemical probe for studying transcriptional regulation in cancers and HIV latency reversal in both cellular and biochemical assays.

Product Specifications

CAS Number

900308-51-2

Product Name Alternative

KL 2, KL2, KL-2, SEC inhibitor KL-2, SEC

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Purity

98.03% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (9.89 mM) ; DMSO:75 mg/mL (224.73 mM)

Smiles

Cc1ccc (Cl) cc1NC (=O) C (\O) =C\C (=O) c1ccc (F) cc1

Molecular Formula

C17H13ClFNO3

Molecular Weight

333.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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