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SHP836

SHP836 is a cell-permeable, allosteric inhibitor of the full-length SHP2 phosphatase with a reported IC50 of 12 μM. It serves as a valuable research tool for investigating SHP2 signaling in cancer and RASopathies, applicable in both cellular and biochemical assays.

Product Specifications

CAS Number

1957276-35-5

Field of Research

Metabolism Research

Smiles

C[C@H]1CN (C[C@@H] (C) N1) c1ncc (c (N) n1) -c1cccc (Cl) c1Cl

Molecular Formula

C16H19Cl2N5

Molecular Weight

352.26

Storage Conditions

-20°C

Notes

For research use only.

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