SR-144528
SR144528 is a potent and selective CB2 receptor antagonist (Ki = 0.6 nM) that also inhibits microsomal ACAT activity (IC50 = 3.6 μM) . This dual activity makes it a valuable research tool for investigating cannabinoid system pharmacology and cholesterol metabolism in both in vitro and in vivo models.
Product Specifications
CAS Number
192703-06-3
Product Name Alternative
SR 144528, SR144528, SR-144528, CannabinoidReceptor, Cannabinoid Receptor, CB2 receptor, CB2
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
Cannabinoid CB2 antagonist
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml, with warming) .
Smiles
[H][C@@]12CC[C@@] (C) (C1) [C@H] (NC (=O) c1cc (-c3ccc (Cl) c (C) c3) n (Cc3ccc (C) cc3) n1) C2 (C) C
Molecular Formula
C29H34ClN3O
Molecular Weight
476.07
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5- (4-Chloro-3-methylphenyl) -1-[ (4-methylphenyl) methyl]-N-[ (1S,2S,4R) -1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide
Available Sizes
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