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SR2211

SR2211 is a potent and selective inverse agonist of the nuclear receptor RORγ, exhibiting an IC50 of 320 nM and a Ki of 105 nM. This small molecule is a valuable research tool for studying Th17 cell biology, autoimmune diseases, and cancer in both cellular and animal models.

Product Specifications

CAS Number

1359164-11-6

Product Name Alternative

RORγ, SR 2211, SR2211, SR-2211

Field of Research

Metabolism Research

Purity

98.20% (May vary between batches)

Solubility

DMSO:90 mg/mL (170.62 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (6.26 mM)

Smiles

OC (c1ccc (c (F) c1) -c1ccc (CN2CCN (Cc3ccncc3) CC2) cc1) (C (F) (F) F) C (F) (F) F

Molecular Formula

C26H24F7N3O

Molecular Weight

527.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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