SR2211
SR2211 is a potent and selective inverse agonist of the nuclear receptor RORγ, exhibiting an IC50 of 320 nM and a Ki of 105 nM. This small molecule is a valuable research tool for studying Th17 cell biology, autoimmune diseases, and cancer in both cellular and animal models.
Product Specifications
CAS Number
1359164-11-6
Product Name Alternative
RORγ, SR 2211, SR2211, SR-2211
Field of Research
Metabolism Research
Purity
98.20% (May vary between batches)
Solubility
DMSO:90 mg/mL (170.62 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (6.26 mM)
Smiles
OC (c1ccc (c (F) c1) -c1ccc (CN2CCN (Cc3ccncc3) CC2) cc1) (C (F) (F) F) C (F) (F) F
Molecular Formula
C26H24F7N3O
Molecular Weight
527.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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