SU16f
SU16f is a potent and selective PDGFRβ inhibitor (IC50 = 10 nM) that blocks PDGFRβ-mediated signaling. Its application in research includes in vitro studies demonstrating inhibition of gastric cancer cell proliferation and migration driven by MSC-conditioned medium, highlighting its utility in oncology and stromal interaction research.
Product Specifications
CAS Number
251356-45-3
Product Name Alternative
3-substituted indolin-2-one 16f, PDGFR1, PDGFR2, PDGFRβ, SU16f, SU-16F, SU 16F
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.69% (May vary between batches)
Solubility
DMSO:25 mg/mL (64.69 mM)
Smiles
C (=C1C=2C (=CC (=CC2) C3=CC=CC=C3) NC1=O) C4=C (C) C (CCC (O) =O) =C (C) N4
Molecular Formula
C24H22N2O3
Molecular Weight
386.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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