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SU16f

SU16f is a potent and selective PDGFRβ inhibitor (IC50 = 10 nM) that blocks PDGFRβ-mediated signaling. Its application in research includes in vitro studies demonstrating inhibition of gastric cancer cell proliferation and migration driven by MSC-conditioned medium, highlighting its utility in oncology and stromal interaction research.

Product Specifications

CAS Number

251356-45-3

Product Name Alternative

3-substituted indolin-2-one 16f, PDGFR1, PDGFR2, PDGFRβ, SU16f, SU-16F, SU 16F

Field of Research

Cardiovascular Research, Signal Transduction

Purity

97.69% (May vary between batches)

Solubility

DMSO:25 mg/mL (64.69 mM)

Smiles

C (=C1C=2C (=CC (=CC2) C3=CC=CC=C3) NC1=O) C4=C (C) C (CCC (O) =O) =C (C) N4

Molecular Formula

C24H22N2O3

Molecular Weight

386.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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