SYM2206
SYM2206 is a low-affinity, non-competitive AMPA receptor antagonist (IC50 = 1.6 μM) that demonstrates anticancer properties. It functions by inhibiting Nav1.6-mediated sustained currents, leading to reduced survival in pancreatic cancer cells in vitro, highlighting its utility in neurobiological and oncology research.
Product Specifications
CAS Number
173952-44-8
Product Name Alternative
AMPAR, Nav1.6 channel, SYM 2206, SYM2206, SYM-2206, SodiumChannel, Sodium Channel
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.80% (May vary between batches)
Solubility
DMSO:100 mg/mL (272.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.92 mM)
Smiles
CCCNC (=O) N1N=C (c2ccc (N) cc2) c2cc3OCOc3cc2C1C
Molecular Formula
C20H22N4O3
Molecular Weight
366.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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