Talazoparib tosylate
Talazoparib tosylate (BMN 673ts) is a potent, orally bioavailable small molecule inhibitor of PARP1 and PARP2. It is widely used in preclinical research, including in vitro cell-based assays and in vivo xenograft models, to investigate targeted therapies for BRCA-mutated breast and ovarian cancers.
Product Specifications
CAS Number
1373431-65-2
Product Name Alternative
PARP2, PARP1, BMN 673ts, BMN673ts
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.24 mM) ; DMSO:100 mg/mL (180.98 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
S (=O) (=O) (O) C1=CC=C (C) C=C1.CN1C ([C@H]2C=3C4=C (N[C@@H]2C5=CC=C (F) C=C5) C=C (F) C=C4C (=O) NN3) =NC=N1
Molecular Formula
C26H22F2N6O4S
Molecular Weight
552.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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